Charge-Enhanced Acidity and Catalyst Activation

Publication Number
136
Citation

Samet, M.; Buhle, J.; Zhou, Y.; Kass, S. R.  J. Am. Chem. Soc., 2015137, 4678–4680. 

Abstract

Acidities are commonly measured in polar solvents but catalytic reactions are typically carried out in nonpolar media. IR spectra of a series of phenols in CCl4 and 1% CD3CN/CCl4 provide relative acidities. Nonprotonated charged substituents with an appropriate counterion are found to enhance their Brønsted acidities and improve catalyst performance by orders of magnitude.

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toc136
DOI
10.1021/jacs.5b01805